Species of Plants Reported to Be Used Traditionally to Treat Diabetes Hhj
Phaseolus multiflorus Willd. Phaseolus mungo L. Parkia speciosa Hassk. Africa, India Pueraria lobata Willd. China Ohwi. Part Used Comments about Activity Phaseolus vulgaris L. Africa, Europe, Seed Pithecellobium dulce India Leaf Pongamia pinnata L. India Flower Pierre Prosopis farcta Macbride Middle East Root Pterocarpus marsupium Africa, India, S. Wood, bark Extracts decrease glucose level in blood. Increase in peripheral utilization of glucose and release of insulin in a way that differs from...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes 1
Amaryllidaceae Lycoris radiata Herb. Dioscorea dumetorum Pax. Africa Dioscorea gracillima Miq. E. Asia Dioscorea japonica Herb. E. Asia Madr. ex. Wall. Smilax canariensis Willd. Canaries Amaryllidaceae Lycoris squamigera Asia Asparagaceae Asparagus gonocladus India Asparagaceae Convallaria majalis L. Asia Part Used Comments about Activity Tuber Reduces glucose in alloxan-treated rabbits Ivorra et al., 1989 Bulb Used to treat diabetes Marles and Farnsworth, 1995 Tuber Dioscorans A to F have...
Insulinomimetic Agents
The need to inject insulin to bypass digestion of the peptide by gastrointestinal enzymes and increase its bioavailability is a major drawback to its acceptability. The insulin receptor is a cell surface protein, so it is theoretically possible that compounds will be discovered that are absorbed orally and can bind and activate the insulin receptor.71 This might be by binding to the insulin-binding sites on the extracellular domain of the insulin receptor or by activating its intracellular...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes
Lauraceae Lauraceae Lauraceae Lauraceae Lauraceae Cinnamomum tamala T. Nees amp Eberm. Cinnamomum zeylanicum Europe Blume Laurus nobilis L. Persea americana Mill. Persea gratissima Gaertn. Phoebe wightii Meisn. Piper cubeba Bojer Piper longum Blume Piper nigrum L. Part Used Comments about Activity Leaf, bark Cinnamaldehyde isolated from bark inhibits aldose reductase Lee, 2002 Bark Extracts decrease blood glucose in alloxan-treated rats Kar et al., 2003 Bark Antinociceptive in vivo Atta and...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Wog
Rhizophora mucronata Tropics, India Aerial parts Casearia glauca Lam. India Bark Casearia esculenta Roxb. India Turnera diffusa Willd. C. America Roxb. amp G. Don Averrhoa bilimbi L. Tropics Biophytum sensitivum L. S.E. Asia All Parkinson Fosberg Ficus benghalensis L. India, E. Asia, Leaf, root Africa bark Used to treat diabetes Marles and Farnsworth, 1995 Used to treat diabetes Marles and Farnsworth, 1995 Root extract is antioxidant in STZ-treated rats Prakasam et al., 2003 Recent research...
Table of Contents
Introduction to Diabetes Plants Used in the Treatment of Monique S.J. Simmonds and Melanie-Jayne R. Howes Preclinical and Clinical Methods for Evaluating Antidiabetic Activity of Plants 83 In Vitro Models for Assessing Antidiabetic Amala Soumyanath nee Raman and Sairavee Srijayanta Ayurvedic, Siddha, and Tribal Venugopal P. Menon and P. Stanely Mainzen Prince Traditional Chinese and Kampo Masayuki Yoshikawa and Hisashi Matsuda Treating Non-Insulin-Dependent Diabetes Mellitus from a Western...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Wpe
Fabaceae Fabaceae Fabaceae Fabaceae Fabaceae Fabaceae Fabaceae Fabaceae Fabaceae Fabaceae Fabaceae Acacia suma Buch.-Ham. Africa, India ex. Voigt Albizia lebbek Benth. Africa, India, Africa, India, Aerial parts Australia Alhagi maurorum Medik. Africa, All Arachis hypogaea L. Asia, America Nut Astragalus membranaceus Asia Fisch. Bunge Bauhinia candicans Benth C. America, S.E. Asia, Butea monosperma Lam. India Taub. Caesalpinia bounducella India Flem. Caesalpinia digyna Rottl. India Part Used...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Pzs
Bambusa nutans Wall. ex. India Munro Panicum miliaceum L. Poa pratensis Pollich Saccharum officinarum L. Africa, C. and S. Juice America Acrocomia mexicana Karw. C. America ex. Mart. Ensete superbum Roxb. India Cheesman Part Used Comments about Activity All Lowers blood glucose Maries and Farnsworth, 1995 Aerial parts Some oat bran concentrate bread products improve glycemic, insulinemic, and lipidemic responses in NIDDM patients Pick et al., 1996 Aerial parts Used to treat diabetes Marles and...
Species of Plants Reported to Be Used Traditionally to Treat 1
Urticaceae Urticaceae Urticaceae Urticaceae Rubus strigosus Michx. Rubus ulmifolius Schott. Sarcopoterium spinosum Middle East Root Spach Cecropia obtusifolia Bertol C. America Leaf, stem Acacia catechu Brandis India, S.E. Asia Stem Acacia melanoxylon R. Br. Africa, India, Seed Australia Acacia modesta Wall India Seed Reduces blood glucose Ivorra et al., 1989 Used to treat diabetes Lust, 1986 Reduces blood glucose level in blood of alloxan-treated rats Lemus et al., 1999 Contains triterpenes...
unmet needs
Treatment of diabetes mellitus poses a number of problems for the individual with the condition Diabetes management requires input from health professionals to achieve optimum management over a lifetime. Often, in middle-aged individuals with longstanding habitually poor diet and exercise regimens, changes in diet and lifestyle are difficult to implement and maintain. Oral drug treatment often requires combinations of drugs with an increased potential for adverse effects. Oral drug treatments...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Gyr
Cucurbitaceae Cucurbitaceae Cucurbitaceae Cucurbitaceae Cucurbitaceae Cucurbitaceae Cucurbitaceae Cucurbitaceae Cucurbitaceae Cucurbitaceae Cyclanthera pedata L. S. America, Schrad E. Africa Gynostemma pentaphyllum Thunb. Mak Lagenaria vulgaris Ser. Luffa acutangula L. Roxb. Luffa aegayptiac Mill. Luffa echinata Roxb. Momordica balsamina L. Momordica charantia L. Momordica cochinchinensis Lour. Spreng. Momordica foetida Schum. Africa, India, C. America, Australia, Middle East Larrea tridentata...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Flp
Polygonatum odoratum China subsp. glaberrimum K. Koch Elenevsky amp A.S. Zernov Dendrobium chrysanthum China Wall.ex. Lindl. Andropogon citratus Hort Asia ex. DC Polygonatum officinale All. Europe, Asia Rhizome Aloe vera L. Burm. f. India, W. Indies, Leaf E. Asia Orchis mascula Crantz. Europe, India, Root Middle East Steroidal glycosides decrease blood glucose and stimulate glycogen synthase. Promotes peripheral sensitivity to insulin rather than altering secretion of insulin Choi and Park,...
Contributors
Health Sciences Department, Biological and Health Sciences Division Universidad Autonoma Metropolitana Iztapalapa, Mexico Diabetes Research, Pharmaceutical Sciences Aston University Birmingham, United Kingdom Ealing Hospital and Imperial College London, United Kingdom Department of Chemistry and Biochemistry Laboratory for Aging and Disease University of Oklahoma Norman, Oklahoma Department of Chemistry and Biochemistry Laboratory for Aging and Disease University of Oklahoma Norman, Oklahoma...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Vld
Cucurbitaceae Cucurbitaceae Cucurbitaceae Benincasa hispida Thunb. India, S.E. Asia Fruit Cogn. Bryonia alba Bull. Asia, Europe, All Bryonia cretica L. Europe Aerial parts Bryonia epigaea Blume India Aerial parts Citrullus colocynthis Middle East All Citrullus lanatus Thunb. Tropics, Fruit Coccinia grandis L. Voigt Africa, India Root Part Used Comments about Activity Bark Used to treat diabetes Marles and Farnsworth, 1995 Gall Grandinin reduces blood glucose in STZ-treated mice Moharram et al.,...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Qno
Moringa ole fera Lam. Middle East Fruit Moringa pterygosperma India L. Gaertn. Salvadora persica L. Middle East Aerial parts Anacardium occidentale L. Tropics, Europe Stem, leaf Poupartia birrea Hochst. Africa Aubrev. Rhus chinensis Mill. E. Asia, India, Aerial parts Sclerocarya birrea A. Rich. Hochst. Niazicin, 1-O-phenyl-a-L-rhamnopyranoside, methyl ate and methyl N- 4- 4'-0-acetyl-a-L-rhamnopyranosyl benzyl carbamate stimulate insulin release Francis et al., 2004 Used to treat diabetes...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Fut
Zygophyllaceae Tribuluks terrestris L. Asia Brassicaceae Brassicaceae Brassicaceae Brassicaceae Brassicaceae Brassicaceae Brassicaceae Brassicaceae Caricaceae Brassica rapa L. Capparis spinosa L. Cleome droserifolia Delile Middle East Webb ex. Prantl. Lepidium ruderale L. Asia Raphanus sativus L. Carica papaya L. amp Bois L.H. Bailey Brassica oleracea L. Europe, India All Nasturtium officinale R. Br. Canaries, India Aerial parts Decreases blood glucose and improves glucose tolerance You and...
molecular mechanisms of insulin action
Insulin exerts its effects on target organs liver, muscle, fat by binding to a cell surface receptor and activating a number of intracellular signaling cascades.7,8 This is an area of intense scientific scrutiny because it is hoped that understanding the mechanism of action of insulin will reveal new drug targets that may be amenable to manipulation by small, nonpeptide agonists. The intracellular signaling cascades activated are, to some extent, tissue specific one mechanism whereby insulin...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Sax
Lamiaceae Lamiaceae Lamiaceae Lamiaceae Lamiaceae Lamiaceae Lamiaceae Lamiaceae Ocimum americanum Sims S.E. Asia Ocimum gratissimum Africa Forssk. Origanum syriacum L. Middle East Origanum vulgare L. Orthosiphon aristatus Miq. S.E. Asia Orthosiphon spiralis Merr. Salvia lavandulifolia Vahl. Europe, C. Salvia miltiorrhiza Bunge. China Salvia officinalis L. Europe Solenostemon rotundifolius Africa Poir. J.K. Morton Teucrium oliverianum R. Middle East Br. Part Used Comments about Activity All Used...
Editor
Amala Soumyanath n e Amala Raman is a classically trained pharmacognosist. She received a pharmacy degree from Chelsea College and a Ph.D. from King's College London University of London, U.K. . She was senior lecturer in pharmacognosy in the Pharmacy Department, King's College London, until 2002, after which she moved to her present position as associate professor, Department of Neurology, Oregon Health amp Science University, Portland. Her research centers on the identification of active...
Insulin Replacement
Insulin deficiency is logically treated by replacing the absent insulin peptide. This is the mainstay of treatment for patients with the absolute insulin deficiency found in type 1 diabetes and is frequently necessary for many patients with type 2 diabetes when they fail to respond to oral drug therapy. Exogenous insulin therapy, given by subcutaneous injection, does not closely match physiological release of insulin. Hypoglycemia may occur when a mismatch occurs between carbohydrate intake and...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Fij
Gentianaceae Gentianaceae Gentianaceae Loganiaceae Loganiaceae Loganiaceae Enicostema hyssopifolium Africa, India All Enicostema litoralis Blume India Swertia chirata Buch. Ham Africa, India All Anthocleista nobilis G. Don Africa Bark Anthocleista vogelii Planch. Africa Root Gelsemium sempervirens L. J. St.-Hil. Strychnos nux-vomica L. India, S.E. Asia Fruit Anthocephalus indicus A. India Rich. Cephalanthus glabratus K. S. America Schum Coffea arabica L. Asia Seed Coutarea latiflora Sess amp...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Mtl
Lamiaceae Teucrium royleanum Wall. India Oleaceae Ligustrum lucidum Ait. China Syringa vulgaris L. Sesamum indicum L. Cistanche tubulosa Wight Africa, India, Asia Cymbalaria muralis India Gaertn. Isoplexis canariensis Steud Canaries Isoplexis isabelliana Webb Canaries Pedicularis rhinanthoides India Larranaga Part Used Comments about Activity Leaf Aqueous extracts lower blood glucose and enhance insulin secretion in STZ-treated rats Esmaeili and Yazdanparast, 2004 All Used to treat diabetes...
selection of species
It is clear that a case can be made for further research on these potentially antidiabetic species. However, how should the plants to study be selected Marles and Farnsworth 1995 suggested that to accelerate research on the antidiabetic activity of plants, five criteria could be used to prioritize the selection of species Traditional use in one or more countries Experimentally determined hypoglycemic activity Lack of detailed information on hypoglycemic constituents Experimental evidence for...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Dze
Cajanus cajan L. Millsp Africa, India Seed Cassia occidentalis L. Cassia sophera L. Ceratonia siliqua L. Cyamopsis tetragonolobus Arabia, India, S. Seed Taub America Eysenhardtia polystachya C. America Sarg. Galega officinalis L. Europe, India Leaf, seed Part Used Comments about Activity Frequently used to treat patients with diabetes, especially in India Grover, 2002 Aerial parts Used to treat diabetes Marles and Farnsworth, 1995 Leaf Extracts reported to have antidiabetic activity Palanichamy...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Ull
Sapotaceae Sapotaceae Sapotaceae Styracaceae Acanthaceae Acanthaceae Acanthaceae Acanthaceae Acanthaceae Acanthaceae Acanthaceae Barringtonia acutangula L. Gaertn. Part Used Comments about Activity Pouteria tomentosa Roxb. India Baehni Dipteracanthus prostratus India Nees Jacobinia suberecta E. S. America Reduces blood glucose Handa et al., 1989 Used to treat diabetes Marles and Farnsworth, 1995 Used to treat diabetes Marles and Farnsworth, 1995 Used to treat diabetes Marles and Farnsworth,...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Aix
S.America, S.E. Leaf, seed Asia, India India, Seed Lupinus termis Forssk. N. Africa Seed Millettia cinerra Benth. Burma Mimosa pudica Mill. Part Used Comments about Activity Root Hydrophobic flavonoids in licorice decrease blood glucose and abdominal fat. These effects may be mediated via peroxisome proliferator-activated receptor-y Nakagawa et al., 2004 Traditionally used to treat diabetes in Ghana but extracts did not have hypoglycemic activity in nondiabetic humans and showed some overt...
Species of Plants Reported to Be Used Traditionally to Treat
Oleandra pistillaris Sw. India C. Chr. Magnoliaceae Magnoliaceae Magnoliaceae Juniperus communis Thunb. Abies pindrow Spach. Pinus densiflora Siebold amp Japan Zucc. Schisandra chinensis Turcz. Baill Talauma ovata A. St. Hil. C. America Europe, India Fruit India Aerial parts Shows hypoglycemic activity in rats Abraham et al., 1986 Glycan ephedrans A, B, C, D, and E and L-ephredrine have antihyperglycemic activity regenerate atrophied pancreatic islets and restore secretion of insulin Xiu et...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Qwk
Euphorbiaceae Euphorbiaceae Euphorbiaceae Euphorbiaceae Euphorbiaceae Euphorbiaceae Euphorbiaceae Euphorbiaceae Passifloraceae Rhizophoraceae Rhizophoraceae Croton niveus Billb. ex. Beurl. Euphorbia hirta L. Glochidion hohenackeri M ll. Arg. Bedd Mallotus philippinensis M ll. Arg. Manihot esculenta Crantz Phyllanthus amarus Schumach. amp Thonn. S. America Australia, India All India Passiflora quadrangularis Tropical Kandelia rheedii Wight amp India Arn. Phyllanthus emblica L. India Seed...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Brb
Solanaceae Solanaceae Solanaceae Solanaceae Part Used Comments about Activity Sieber. ex. Spreng. Ipomoea aquatica Forssk. America, E. Ipomoea batatas L. Lam. America, tropics Capsicum annuum L. Capsicum frutescens L. Used to treat diabetes Marles and Farnsworth, 1995 Leaf Aqueous extract of leaves is as effective as tolbutamide at reducing blood glucose level in Wistar rats Malalavidhane et al., 2001 Leaf Decreases blood glucose in patients with type 2 diabetes Ludvik et al., 2004 Leaf...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Ypz
Dodonaea viscosa Jacq. India Ailanthus altissima Swingle India Eurycoma longifolia Jack Africa Abelmoschus manihot L. India Medik. Decaschistia crotonifolia India Gossypium herbaceum L. Africa, India Hibiscus rosa-sinensis L. India Hibiscus tiliaceus L. Malva verticillata L. Salmalia malabarica Schott India, E. Asia, amp Endl. Australia Part Used Comments about Activity Fruit Used to treat diabetes Marles and Aerial parts Used to treat diabetes Marles and Farnsworth, 1995 Bark Used to treat...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Gpl
Rosaceae Rosaceae Rosaceae Rosaceae Rosaceae Morus australis T. Hotta E. Asia Morus nigra L. India, Asia, Europe Rhamnus purshiana DC. C. America Ziziphus mauritiana Lam. Tropics Alchemilla vulgaris Wight Europe Cotoneaster aitchisoni C.K. India Schneid. Eriobotrya japonica India Thunb. Lindl. Poterium ancistroides Guir. Europe ex. Nym. Prunus amygdalus Stokes Universal Prunuspersica L. Batsch S.E. Asia, India Leaf Pyrus communis L. Rosa brunonii Lindl. Aerial parts Rosa canina L. Europe Fruit...
background
The Ebers Papyrus written in approximately 1550 b.c. provides the earliest documentation about the use of plants in the treatment of conditions associated with diabetes Bailey and Day, 1989 . In India, the early Ayurvedic texts such as the Sushruta Samhita and the Charaka Samhita written in the 4th to 5th century b.c. describe the use of about 760 and 500 species of medicinal plants, respectively, including those prescribed for conditions such as glycosuria, polyphagia, and polyuria associated...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Dku
Scrophulariaceae Rehmannia glutinosa Libosch Scrophulariaceae Rehmannia lutea Maxim. Scrophulariaceae Scoparia dulcis L. India, Africa Scrophulariaceae Scrophularia buergeriana China Miq. Scrophulariaceae Scrophularia ningpoensis China Hemsl. Scrophulariaceae Striga gesnerioides Vatke India ex. Engl. Scrophulariaceae Torenia asiatica Herb. India Madr. ex. Wall. Gmelina arborea Roxb. Convolvulaceae Argyreia cuneata Ker. Gawl. Convolvulaceae Argyreia nervosa Bojer India Convolvulaceae Calystegia...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Cjt
Combretaceae Terminalia chebula Retz. India, S.E. Asia Fruit Lythraceae Lythraceae Lythraceae Lythraceae Lagerstroemia parviflora Asia, India, Roxb. root, seed Mediterranean Stem, flower Melastomataceae Memecylon umbellatum India Blume Eucalyptus citriodora Hook Africa, India Leaf Eucalyptus globulus Labill. Africa, America Leaf Eugenia jambolana Lam. Africa Seed, bark Hexachlamys edulis O. S. America Berg Kausel amp D. Legrand Myrcia uniflora Bard. Robr. Myrtus communis L. Africa Leaf, stem...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Jmi
Spinacia oleracea L. Africa, Europe, Lophophora williamsii Salm-Dyck J.M. Coult. Opuntia ficus-indica L. Africa, Europe, Aerial parts Bougainvillea spectabilis India Willd. Salpianthus arenarius C. America Humb. amp Bonpl. Polygala senega L. Asia Part Used Comments about Activity Aerial parts Reduces blood glucose in alloxan-treated dogs Handa et al., 1989 Extracts have antidiabetic activity Marles and Farnsworth, 1995 Extracts have antidiabetic activity, but plant is toxic Marles and...
Where Do We Go New Antidiabetic Plants
Diabetes mellitus diabetes is a disease of worldwide significance and increasing prevalence. Plant materials have played an important role in the traditional treatment of diabetes, particularly the type II non-insulin-dependent form. In many regions of the world, herbal remedies continue to be more accessible and affordable than conventional drugs and represent the first line of treatment available to a diabetes patient. Concurrently, within societies with well-developed, modern health care...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Hkk
Bignoniaceae Bignoniaceae Bignoniaceae Heterophragma Indonesia quadriloculare K. Schum Spathodea campanulata Asia Buch.-Ham. ex. DC. Stereospermum suaveolens India DC. Tecoma mollis H.B.K. Africa, India Calamintha macrostema C. America Benth. Calamintha officinalis Morocco Moench Cedronella canariensis Canaries Webb amp Berthel. Clerodendranthus spicatus Brunei Thunb. C.Y. Wu Leonotis leonurus L. R. Africa Br. Part Used Comments about Activity Aerial parts Extracts have antidiabetic activity...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Apz
Ranunculaceae Coptis chinensis Franch. E. Asia Coptis deltoidea C.Y. Cheng et Hsiao Hydrastis canadensis L. Nigella sativa L. Nelumbonaceae Nelumbo nucifera Gaertn. India Amaranthaceae Achyranthes aspera L. Africa, India, Amaranthaceae Aerva sanguinolenta Blume S.E. Asia Decreases serum glucose, berberine has hypoglycemic activity Chen and Xie, 1986 Decreases serum glucose, berberine has hypoglycemic activity Chen and Xie, 1986 Used to treat diabetes Maries and Farnsworth, 1995 Used to treat...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Kiy
Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Cirsium pascuarense H.B.K. Spreng. Elytropappus rhinocerotis Africa Less Helianthus annuus L. N. America Helianthus tuberosus L. N. America, Inula racemosa Hook f. C. America, India Inula viscosa Dryand. Middle East Matricaria aurea Sch. Bip. Middle East Neurolaena lobata R. Br. C. America Psacalium decompositum C. America H.B.K. Cass...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Yzc
Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Bidens leucantha Willd. C. America Cacalia decomposita A. C. America Gray Calea zacatechichi C. America Schlecht Cirsium dipsacolips Matsum Cirsium ochrocentrum A. Gray Root, stem Aerial parts Aerial parts Centaurea calcitrapa L. Africa, Europe, Aerial parts India Centaurea corcubionensis Europe Leaf, flower Centaurea melitensis L. Canaries, Aerial parts Centaurea salmantica...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Sxv
Burseraceae Meliaceae Meliaceae Rutaceae Commiphora molmol Engl. Middle East ex. Tschirch Amoora wallichi Bulm. F. Atalantia racemosa Wight India et Arn albiflora Rchb. Citrus aurantium L. Subtropics Phellodendron amurense India, China Rupr. Phellodendron chinensis Asia Schneid Azadirachta indica A. Juss India, E. Asia, Leaf, seed, Aegle marmelos Correa India Leaf, root, Feronia limonia Swingle India Fruit Murraya koenigii L. Africa, India Leaf Zanthoxylum alatum Roxb. Africa, India, E. Stem...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Nhs
Wall. ex. Spreng. Hedychium spicatum Lodd. India Zingiber officinale Rose. Tropics, India All Zingiber zerumbet Rosc. India ex. Sm Chloroform extract of flowers reduces blood glucose in alloxan-treated rats Pari and Umamaheswari, 2000 Used to treat diabetes Sussman, 1980 Reduces blood glucose in rabbits Akhtar et al., 2002 Extracts have hypoglycemic activity Marles and Farnsworth, 1995 Extracts have hypoglycemic activity Marles and Farnsworth, 1995 Forms part of a mixture, hyponidd, that...
where do we go next
When prioritizing species that need further study, the criteria used by Marles and Farnsworth 1995 can still apply, but more use should be made of taxonomic information about the relationship among plants' families and genera. Molecular data have enabled significant advances to be made in understanding of the phylogenetic relationships among different plant families Chase, 2005 . Species used to treat diabetes can be found distributed throughout the plant kingdom Figure 2.1 . However, some...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Wza
Stevia rebaudiana Bert. Indonesia Hemsl. Taraxacum officinale F.H. Europe, India, Wigg Africa Trixis radialis L. Kuntze C. America Verbesina crocata Less. C. America Cav. A. Gray Verbesina persicifolia DC. C. America Xanthium strumarium Patr. Africa, India, Europe Platycodon grandiflorum China Jacq. A. DC. Valeriana edulis Nutt C. America Valeriana mexicana DC. C. America Valeriana officinalis L. C. America Part Used Comments about Activity Used to treat diabetes Marles and Farnsworth, 1995...
Species of Plants Reported to Be Used Traditionally to Treat Diabetes Bqa
Asteraceae Asteraceae Asteraceae Asteraceae Asteraceae Atractylodes macrocephala China Koidz. Part Used Comments about Activity Panax quinquefolium L. N. America, E. Root Asia Ainsliaea latifolia D. Don India Sch. Bip. Artemisia abyssinica Sch. Arabia All Artemisia herba-alba Asso. Middle East Aerial parts Saponins Li et al., 2004 , and polysaccharides, quinquefolans A, B, and C Oshima et al., 1987 , have antidiabetic activity Extracts used to treat diabetes Marles and Farnsworth, 1995 Used...