P Vxi
Primary Prevention Diabetes Program, Madras, India 262 persons with family history of diabetes, followed for at least 4 years, pre-post analysis. Outcome diabetes Diet High-carbohydrate, low-fat 20 . Exercise primarily 30 minutes per day walking Persons who increased weight versus lost weight or kept stable weight were 5.1 2.6-13.9 times more likely to develop diabetes, adjusted for baseline glucose and gender. Second analysis of similar smaller subset119 found persons with normal OGTT more...
P Vhp
Nolan et al 1994216 San Diego, CA, USA Troglitazone N 12 Troglitazone lower fasting and OGTT Allocation was masked. Small Ia nondiabetic obese 200 mg, bid glucose and insulin levels, increased numbers, short follow-up no follow-up 3 months. Outcome OGTT, clamp Weight maintenence diet and physical activity IGT, Los Angeles, CA, 42 post-GDM women aged x 33 yrs follow-up 3 months. Outcome OGTT, FSIGT Multicenter study of Troglitazone in IGT 51 subjects aged 24 77 x 47 years with IGT follow-up 3...
USA Umi
25 698 persons. Outcome diabetes mortality Gothenburg, Sweden 1154 women. Outcome clinical diabetes or fasting glucose gt 7.0 mmol L Seven Countries Study, Finnish and Dutch cohorts 338 nondiabetic men, 1970-1990. Outcome 2 h glucose Rotterdam, Netherlands, general practice 175 normoglycemic persons. Outcome OGTT, IGT diabetes Rotterdam, Netherlands, general practice 175 normoglycemic persons. Outcome OGTT, IGT diabetes San Antonio Heart Study, Texas, USA 1093 Mexican-American and nonHispanic...
Info Toz
0 total 0 fiber 0 sucrose glycemic index - Potassium, calcium, magnesium gt 5 fruit or vegetable servings day
Oral Glucose Tolerance Test
The oral glucose tolerance test OGTT has for many years been the accepted standard for the diagnosis of diabetes. It is, however, time consuming and inconvenient requiring considerable preparation. Many would therefore regard it as unsuitable for widespread use among people with risk factors for diabetes. Unless conducted in the inpatient setting, the recent dietary intake and duration of the pre-test fast cannot be standardised in the way the protocol demands, and these factors can affect the...
References
1. Major RM 1954 A History of Medicine. Oxford Blackwell . p. 67. 2. Zimmet P 1997 The challenge of diabetes - diagnosis, classification, 'Coca-colonization', and the diabetes epidemic. In Fischer EP, Moller G eds The Medical Challenge Complex Traits. Munchen Piper, pp. 55-110. 3. Himsworth HP 1936 Diabetes mellitus its differentiation into insulin-sensitive and insulin-insensitive types. Lancet 1 117-20. 4. Bornstein J, Lawrence RD 1951 Plasma insulin in human diabetes mellitus. Br. Med. J. 2...
P Nhh
Early Diabetes Intervention Trial EDIT EDIT is a six-year, prospective, randomized, placebo-controlled study in subjects with two consecutive fasting plasma glucose levels in the range 5.5-7.7 mmol L 100-139 mg dl . Nine UK clinical centers have recruited 631 subjects. The primary aim of the trial is to determine whether deterioration in glycemic tolerance towards diabetes can be delayed or prevented using the alpha-glucosidase inhibitor acarbose or the biguanide metformin, in a 2 x 2 factorial...
Contributors List
Diabetes Trials Unit, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6EH, UK Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0607, USA Medicine, Obstetrics and Gynaecology, and Physiology and Biophysics, USC Keck School of Medicine, 6602 General Hospital, 1200 N States Street, Los Angeles, CA 90089-9317, USA 1500 East Medical Center Drive, Division of Cardiology, Level B1, Ann Arbor, Michigan 48109, USA Office of the WHO...
Info Iqm
120 men aged 25-55 years x 45 with borderline glucose tolerance follow-up 2 years. Outcome OGTT 0.85g bid G B N 29 Placebo N 33 204 men with borderline glucose tolerance aged 40-64 years x 57 follow-up 5 yrs. Outcome diabetes incidence 73 persons with borderline or chemical diabetes aged 23-74 x 54 follow-up 5 yrs. Outcome OGTT 457 subjects with high waist-hip ratio, aged 120 g day carbohydrate Phenformin N 49 Biguanide no effect on glucose and insulin significant weight loss. Glibenclamide no...
Autoantibodies
A number of circulating autoantibodies to islet cell markers may be detected at diagnosis of type 1 diabetes. Indeed, current classification of diabetes uses the presence of autoantibodies to define type 1 diabetes or autoimmune diabetes the exception being those individuals prone to ketoacidosis but without antibodies, classified as type 1 idiopathic 33. The autoantibodies include cytoplasmic islet cell antibodies ICA , insulin autoantibodies IAA , and antibodies directed against glutamic acid...